Validation of the Subarachnoid Haemorrhage International Trialists' (SAHIT) score: single centre retrospective cohort comparison study
EANS Academy. Baig Mirza A. 09/27/19; 276140; EP01080
Dr. Asfand Baig Mirza
Dr. Asfand Baig Mirza

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Objectives: This study attempts to externally validate the SAHIT score (a prognostication score for subarachnoid haemorrhage) using a cohort from a large UK neurovascular centre.
Methods: A retrospective review of prospectively collected data was carried out on all patients above the age of 18 diagnosed with aneurysmal SAH between 2006 and 2017. 1,411 cases were identified. 324 patients, who matched all the SAHIT scoring criteria, were used for this analysis. The analysis was undertaken by an independent statistician (Statsconsultancy Ltd). The pre-defined SAHIT models were evaluated for discrimination and calibration and the predicted probabilities of outcome were compared to the observed ones.
Results: Our study demonstrated poor discrimination for both the morbidity and mortality models. Furthermore, calibration was poor, with the score underestimating both morbidity and mortality.
Conclusion: Our study would suggest that the SAHIT score cannot be used in its present form for generalization to a UK neurovascular practice. Prior to applying such a score in a clinical setting further validation is required against a multicenter cohort, for example, the UK and Ireland Subarachnoid Haemorrhage Database.
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