Save
Quality of life following endoscopic endonasal surgery for pituitary macroadenoma
EANS Academy. Sufaro Y. 09/26/19; 276137; EP04060
Yuval Sufaro
Yuval Sufaro

Access to this content is reserved for EANS members and attendees of this event. Click here to become an EANS member and gain your access to the full content of the EANS Academy


Abstract
Discussion Forum (0)
Rate & Comment (0)
Background: In light of many studies which demonstrated endoscopic transsphenoidal surgery (TSEES) as a safe and efficient surgical option, it has become the standard treatment choice for pituitary macroadenoma (PMA). Nevertheless, literature describing quality of life assessment for patients following this surgery is sparse.
Aim: To asses patients´ quality of life, as perceived by the patients themselves, after undergoing TSEES for PMA. In particular, to assess the impact of TSEES on nasal related aspects of quality of life.
Methods: Demographic and clinical data of 26 patients who underwent ETSS for resection of PMA (pre and post-surgery) were retrieved retrospectively. Post-surgical quality of life was assessed via standardized questionnaires.
Results: Total of 52 transnasal neurosurgeries took place in our institution in the years 2016-2018. Of them 26 patients who underwent transnasal transsphenoidal endoscopic resection of pituitary macroadenoma were included in the current study. Averaged age of the patients was 56±14 years, most of them were females (14), averaged Karnofsky score 85±10. 20 (77%) presented with visual fields deficits, cavernous sinus invasion was present in 22 cases (85%), hormonal deficiency was present in 20 (77%), 4 (15%) were secreting.
Average score for SF-36 health survey score was 51±20, highest score was registered for ´physical role functioning´ and ´mental health´ (64 each), and lowest for ´emotional role functioning ´(30).
Average post-surgery SNOT-22 questionnaire score was 1.4 ± 1.6. The average result for the extra twenty third question - 'what is the level of improvement regarding nasal related symptoms after surgery?', was 2.2 ± 1.5 (1- significant improvement, 5 - significant worsening).
Since 2018 we replaced the technique of naso-septal flap, for closure with sphenoidal sinus mucosa. The later technique seems to be superior regarding subjective improvement after surgery 2.5 vs. 1.3 (but without statistical significance, P=0.26, T-test).
Background: In light of many studies which demonstrated endoscopic transsphenoidal surgery (TSEES) as a safe and efficient surgical option, it has become the standard treatment choice for pituitary macroadenoma (PMA). Nevertheless, literature describing quality of life assessment for patients following this surgery is sparse.
Aim: To asses patients´ quality of life, as perceived by the patients themselves, after undergoing TSEES for PMA. In particular, to assess the impact of TSEES on nasal related aspects of quality of life.
Methods: Demographic and clinical data of 26 patients who underwent ETSS for resection of PMA (pre and post-surgery) were retrieved retrospectively. Post-surgical quality of life was assessed via standardized questionnaires.
Results: Total of 52 transnasal neurosurgeries took place in our institution in the years 2016-2018. Of them 26 patients who underwent transnasal transsphenoidal endoscopic resection of pituitary macroadenoma were included in the current study. Averaged age of the patients was 56±14 years, most of them were females (14), averaged Karnofsky score 85±10. 20 (77%) presented with visual fields deficits, cavernous sinus invasion was present in 22 cases (85%), hormonal deficiency was present in 20 (77%), 4 (15%) were secreting.
Average score for SF-36 health survey score was 51±20, highest score was registered for ´physical role functioning´ and ´mental health´ (64 each), and lowest for ´emotional role functioning ´(30).
Average post-surgery SNOT-22 questionnaire score was 1.4 ± 1.6. The average result for the extra twenty third question - 'what is the level of improvement regarding nasal related symptoms after surgery?', was 2.2 ± 1.5 (1- significant improvement, 5 - significant worsening).
Since 2018 we replaced the technique of naso-septal flap, for closure with sphenoidal sinus mucosa. The later technique seems to be superior regarding subjective improvement after surgery 2.5 vs. 1.3 (but without statistical significance, P=0.26, T-test).
Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.



Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.


Save Settings