Save
Rhinological outcome in endoscopic transnasal skull base surgery - a prospective study
EANS Academy. Conrad J. 09/26/19; 276063; EP04061
Jens Conrad
Jens Conrad

Access to this content is reserved for EANS members and attendees of this event. Click here to become an EANS member and gain your access to the full content of the EANS Academy


Abstract
Discussion Forum (0)
Rate & Comment (0)
The sino-nasal outcome has often been neglected besides major criteria such as tumor resection, ophthalmological and endocrinological outcome in transnasal skull base surgery. In this prospective study we review a two and a half-year-collective regarding the rhinological outcome.
Since October 2015 a number of 82 patients (47 m, 35 f, median age 55y) matched the inclusion criteria and were treated via a transnasal endoscopic approach (binostril n=79, mononostril n=3). Primary endpoint is change in olfactory function, secondary nose breathing ability. Other than pituitary adenoma 4 Rathke cleft cysts, 2 colloid cysts, 1 mucocele, 1 craniopharyngeoma and 1 clivuschordoma were histologically found. The study participants are investigated by odor testing ('Sniffin´sticks'), rhinomanometry and endoscopic inspection before and six months after surgery. Moreover quality of life is measured before, right after and six months after surgery with a standardized questionnaire (SNOT-20).
7,0% of the patients underwent previous transsphenoidal surgery, in addition 12,8% had previous septum-, pansinus or combined nasal surgery. Prior to surgery (n=82) the average odor was found to be 30,75 (≥31 = normosmia), in the post interventional examination (n=75) the average increased to 33,08 (p< 0,001). Rhinomanometric examination of binostril nasal airflow showed an average of 596,90 ml/s on inspiration [range: 109,00-1446,00 ml/s] before, and an increase to 729,17 ml/s on inspiration [range: 266,00-1390,00 ml/s] within the inspection interval. SNOT-20 symptom scores showed an improvement right after and six months after surgery (score 59 and 51 vs. 68 before surgery). Due to our endoscopic observations (synechia, crusting, defects of nasal septum) we postulate a relationship to sensitively dealing with vital mucosa and restrictive use of bipolar coagulation.
Besides other relevant clinical markers the rhinological outcome, as it highly impacts on patients quality of life, should also be considered in clinical routine in transnasal skull base surgery.
The sino-nasal outcome has often been neglected besides major criteria such as tumor resection, ophthalmological and endocrinological outcome in transnasal skull base surgery. In this prospective study we review a two and a half-year-collective regarding the rhinological outcome.
Since October 2015 a number of 82 patients (47 m, 35 f, median age 55y) matched the inclusion criteria and were treated via a transnasal endoscopic approach (binostril n=79, mononostril n=3). Primary endpoint is change in olfactory function, secondary nose breathing ability. Other than pituitary adenoma 4 Rathke cleft cysts, 2 colloid cysts, 1 mucocele, 1 craniopharyngeoma and 1 clivuschordoma were histologically found. The study participants are investigated by odor testing ('Sniffin´sticks'), rhinomanometry and endoscopic inspection before and six months after surgery. Moreover quality of life is measured before, right after and six months after surgery with a standardized questionnaire (SNOT-20).
7,0% of the patients underwent previous transsphenoidal surgery, in addition 12,8% had previous septum-, pansinus or combined nasal surgery. Prior to surgery (n=82) the average odor was found to be 30,75 (≥31 = normosmia), in the post interventional examination (n=75) the average increased to 33,08 (p< 0,001). Rhinomanometric examination of binostril nasal airflow showed an average of 596,90 ml/s on inspiration [range: 109,00-1446,00 ml/s] before, and an increase to 729,17 ml/s on inspiration [range: 266,00-1390,00 ml/s] within the inspection interval. SNOT-20 symptom scores showed an improvement right after and six months after surgery (score 59 and 51 vs. 68 before surgery). Due to our endoscopic observations (synechia, crusting, defects of nasal septum) we postulate a relationship to sensitively dealing with vital mucosa and restrictive use of bipolar coagulation.
Besides other relevant clinical markers the rhinological outcome, as it highly impacts on patients quality of life, should also be considered in clinical routine in transnasal skull base surgery.
Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.



Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.


Save Settings