Spontaneous intracerebral hemorrhage in a plateau area: a study based on the Tibetan population
EANS Academy. LIU X. 09/25/19; 275520; EP01127
Dr. XUYANG LIU
Dr. XUYANG LIU

Access to this content is reserved for EANS members and attendees of this event. Click here to become an EANS member and gain your access to the full content of the EANS Academy


Abstract
Discussion Forum (0)
Rate & Comment (0)
Objective: To reveal the characteristics of spontaneous intracerebral hemorrhage (sICH) in a plateau area based on the Tibetan population.
Methods: Data of Tibetan and Han patients (control group) with sICH treated at our center from January 2013 to April 2017 were retrospectively reviewed.
Results: A total of 122 Tibetan and 927 Han patients were included. Compared with Han patients, Tibetan patients were older (54.7±11.2 vs. 50.9±18.3 years, P=0.027), exhibited higher male-to-female ratios (73.8% vs. 55.0%, P < 0.001),were more overweight (22.1% vs. 13.1%, P=0.007) had more smokers (36.9% vs. 20.5%, P < 0.001), had a higher concentration of hemoglobin (163.7±17.6 vs. 134.8±20.2 g/L, P < 0.001), and included a higher number of patients with hypertension (83.6% vs. 60.5%, P < 0.001), diabetes mellitus (19.2% vs. 9.3%, P =0.002), and prior hemorrhagic stroke (9.0% vs. 2.0%, P < 0.001). Tibetan patients also experienced more brainstem hemorrhage (11.5% vs. 5.1%, P=0.039) in the infratentorial region and had a higher risk of in-hospital complications resulting from hematoma enlargement (20.5% vs. 10.4%, P=0.002) and cerebral infarction (59.0% vs. 9.7%, P < 0.001). During a 6-month follow-up period, they had higher rates of unfavorable outcomes and case mortality (P < 0.05). A multivariable analysis adjusted for confounding factors revealed that the Tibetan race was positively associated with unfavorable clinical outcomes in sICH patients (P < 0.05).
Conclusion: Tibetan sICH patients from the plateau area presented unique characteristics in their baseline measurements, incidence of comorbidities, hematoma location, risk of in-hospital complications, and clinical outcomes compared with Han patients. The Tibetan race was positively associated with unfavorable 6-month outcomes in ICH patients.
Objective: To reveal the characteristics of spontaneous intracerebral hemorrhage (sICH) in a plateau area based on the Tibetan population.
Methods: Data of Tibetan and Han patients (control group) with sICH treated at our center from January 2013 to April 2017 were retrospectively reviewed.
Results: A total of 122 Tibetan and 927 Han patients were included. Compared with Han patients, Tibetan patients were older (54.7±11.2 vs. 50.9±18.3 years, P=0.027), exhibited higher male-to-female ratios (73.8% vs. 55.0%, P < 0.001),were more overweight (22.1% vs. 13.1%, P=0.007) had more smokers (36.9% vs. 20.5%, P < 0.001), had a higher concentration of hemoglobin (163.7±17.6 vs. 134.8±20.2 g/L, P < 0.001), and included a higher number of patients with hypertension (83.6% vs. 60.5%, P < 0.001), diabetes mellitus (19.2% vs. 9.3%, P =0.002), and prior hemorrhagic stroke (9.0% vs. 2.0%, P < 0.001). Tibetan patients also experienced more brainstem hemorrhage (11.5% vs. 5.1%, P=0.039) in the infratentorial region and had a higher risk of in-hospital complications resulting from hematoma enlargement (20.5% vs. 10.4%, P=0.002) and cerebral infarction (59.0% vs. 9.7%, P < 0.001). During a 6-month follow-up period, they had higher rates of unfavorable outcomes and case mortality (P < 0.05). A multivariable analysis adjusted for confounding factors revealed that the Tibetan race was positively associated with unfavorable clinical outcomes in sICH patients (P < 0.05).
Conclusion: Tibetan sICH patients from the plateau area presented unique characteristics in their baseline measurements, incidence of comorbidities, hematoma location, risk of in-hospital complications, and clinical outcomes compared with Han patients. The Tibetan race was positively associated with unfavorable 6-month outcomes in ICH patients.
Code of conduct/disclaimer available in General Terms & Conditions

By clicking “Accept Terms & all Cookies” or by continuing to browse, you agree to the storing of third-party cookies on your device to enhance your user experience and agree to the user terms and conditions of this learning management system (LMS).

Cookie Settings
Accept Terms & all Cookies