Save
Glioblastoma associated with an arteriovenous malformation
Author(s): ,
J. Delaunois
Affiliations:
UCL, Neurosurgical Department, Brussels, Belgium; CHR Namur, Neurosurgical Department, Namur, Belgium
,
J. Gonzalez
Affiliations:
CHR Namur, Neurosurgical Department, Namur, Belgium
,
G. Milbouw
Affiliations:
CHR Namur, Neurosurgical Department, Namur, Belgium
G. Koerts
Affiliations:
UCL, Neurosurgical Department, Brussels, Belgium; CHR Namur, Neurosurgical Department, Namur, Belgium
EANS Academy. Delaunois J. Oct 21, 2018; 226100; EP3070
Dr. Julien Delaunois
Dr. Julien Delaunois
Login now to access Regular content available to all registered users.

Access to Privileged content is currently a membership benefit.

Click here to join EANS or renew your membership.
Abstract
Discussion Forum (0)
Rate & Comment (0)
Introduction

There are few reports in the literature concerning the association between glioblastoma (GBM) and arteriovenous malformation (AVM). We present a case of a GBM associated with an AVM and responsible of two hemorrhages.

Case report

A right-handed 58-year-old male patient was brought to the emergency department for an acute confused state with agitation. He was presenting symptoms of mesiotemporal epilepsy, like déjà vu episodes and olfactory hallucinations for six months. The cerebral CT-scan showed a right temporal hemorrhage and on angiographic sequences was identified a tangle of small vessels with an early venous drainage. A digital subtraction angiography was performed and does not show any vascular access authorizing a selective embolization. The patient was operated three weeks after the hemorrhage with a right temporal approach. The presumed vascular lesion was removed “en bloc” and there was no particular intraoperative finding, except a large thrombosed vein. Five days after the surgery, the patient presented a second hemorrhage requiring a reoperation.

Results and discussion

The anatomopathological analysis revealed the presence of astrocytic glial cells with some necrosis areas. There were also some vascular structures with angiomatous characteristics. Several hypothesis have been made about GBM associated with an AVM: fortuitous association, combined or sequential lesions. Another hypothesis is the development of the AVM due to the surexpression of vascular endothelial growth factor (VEGF) by the glioma.

Conclusion
We report a rare case of GBM associated with an AVM, illustrating the necessity to be aware about atypical hemorrhage locations and to perform in these cases a MRI to exclude a neoplastic lesion.
Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.



Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.


Save Settings